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Small molecules comprising two mononucleotides, adenosine monophosphate (AMP) and nicotinamide mononucleotide (NMN); oxidized and reduced nicotinamide adenine dinucleotides in their unphosphorylated (NAD+ or NADH) and phosphorylated (NADP+ or NADPH) forms.
Nicotinamide N-oxide (CAS No 1986-81-8) is a compound utilized in biomedical research particularly in the fields of enzymology and drug development It originates from the oxidation of nicotinamide a form of vitamin B3 The compound primarily targets pathways involved in cellular metabolism and oxidative stress responses Its mechanism of action includes modulating the activity of enzymes such as poly(ADP-ribose) polymerases impacting DNA repair processes and cellular energy homeostasis In vitro it exhibits activity in the nanomolar to low micromolar range making it suitable for detailed biochemical studies Typical applications include experiments in cell models and animal studies to investigate metabolic pathways assess oxidative stress and screen for potential drug candidates Experimental concentrations typically depend on the specific research design allowing for flexibility in various investigative contexts
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Nicotinamide riboside chloride (standard) is an analytical standard of nicotinamide riboside chloride used for research and analytical applications. It is a high-purity NAD+ precursor and source of vitamin B3, supplied as a solid for quantitation, method validation, and metabolic studies.
High purity suitable for analytical and research use.
Available in multiple small sizes for use as standards.
CAS 23111-00-4 provides unambiguous compound identification.
Molecular weight and formula provided for accurate calculations.
Applicable in studies of NAD+ metabolism and sirtuin activation.
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Nicotinamide riboside malate is a salt of nicotinamide riboside and malic acid used as an NAD+ precursor and source of vitamin B3. It is employed in biochemical and cellular research to elevate cellular NAD+ levels, probe sirtuin-mediated pathways, and study metabolic and neuroprotective effects in vitro and in vivo models.
Orally active NAD+ precursor
Raises cellular NAD+ levels
Activates sirtuin pathways
Useful for metabolic and neuroprotection studies
Stable malate salt suitable for biochemical assays
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Nicotinamide riboside chloride is the chloride salt of nicotinamide riboside, a bioavailable precursor of nicotinamide adenine dinucleotide (NAD+) used in biochemical and cell biology research to elevate cellular NAD+ levels and probe NAD+-dependent pathways. It is supplied as a high-purity, crystalline white to off-white solid suitable for in vitro and analytical applications.
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Nicotinamide riboside chloride is the chloride salt of nicotinamide riboside, a vitamin B3-derived NAD+ precursor provided as a research-grade white to off-white powder for biochemical and metabolic studies. It is used to elevate cellular NAD+ levels and to investigate sirtuin activation, energy metabolism, and aging-related pathways.
Increases cellular NAD+ levels.
Activates sirtuin proteins SIRT1 and SIRT3.
Chloride salt form with good aqueous solubility.
Suitable for in vitro and in vivo metabolic research.
High-purity, batch-verified material for reproducible results.
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NAD ( -DPN -NAD -Nicotinamide Adenine Dinucleotide nicotinamide adenine dinucleotide) is a coenzyme composed of ribosylnicotinamide 5 -diphosphate coupled to adenosine 5 -phosphate by pyrophosphate linkage
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The nicotinamide N-methyltransferase (NNMT) protein catalyzes the methylation of nicotinamide using S-adenosyl-L-methionine to form N1-methylnicotinamide NNMT affects pluripotent embryonic stem cell development and acts as a metabolic regulator affecting adipose tissue energy expenditure gluconeogenesis and cholesterol biosynthesis Nicotinamide N-Methyltransferase/NNMT Protein Human (His) is the recombinant human-derived Nicotinamide N-Methyltransferase/NNMT protein expressed by E coli with C-His labeled tag
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